2022
MicroRNA-138 Abates Fibroblast Motility with Effect on Invasion of Adjacent Cancer Cells – PubMed (nih.gov) Front Oncol. 2022 Mar 17;12:833582. doi: 10.3389/fonc.2022.833582. eCollection 2022.
2021
Knowledge, opinions, and practices related to oral cancer prevention and oral mucosal examination among dentists in Moldova, Belarus and Armenia: a multi-country cross-sectional study – PubMed (nih.gov) BMC Oral Health. 2021 Dec 18;21(1):652. doi: 10.1186/s12903-021-02011-2.
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs – PubMed (nih.gov) Front Bioeng Biotechnol. 2021 Nov 30;9:783468. doi: 10.3389/fbioe.2021.783468. eCollection 2021.
Profiling and Functional Analysis of microRNA Deregulation in Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma Depicts an Anti-Invasive Role of microRNA-204 via Regulation of Their Motility – PubMed (nih.gov) Int J Mol Sci. 2021 Nov 4;22(21):11960. doi: 10.3390/ijms222111960.
Predicting intention of Norwegian dental health-care workers to use nanomaterials: An application of the augmented theory of planned behavior – PubMed (nih.gov) Eur J Oral Sci. 2021 Dec;129(6):e12821. doi: 10.1111/eos.12821. Epub 2021 Nov 2.
EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1 – PubMed (nih.gov) Commun Biol. 2021 Nov 1;4(1):1237. doi: 10.1038/s42003-021-02744-4.
Analysis of Salivary Mycobiome in a Cohort of Oral Squamous Cell Carcinoma Patients From Sudan Identifies Higher Salivary Carriage of Malassezia as an Independent and Favorable Predictor of Overall Survival – PubMed (nih.gov) Front Cell Infect Microbiol. 2021 Oct 12;11:673465. doi: 10.3389/fcimb.2021.673465. eCollection 2021.
Targeted Next-Generation Sequencing of Cancer-Related Genes in a Norwegian Patient Cohort With Head and Neck Squamous Cell Carcinoma Reveals Novel Actionable Mutations and Correlations With Pathological Parameters – PubMed (nih.gov) Front Oncol. 2021 Sep 24;11:734134. doi: 10.3389/fonc.2021.734134. eCollection 2021.
Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients – PubMed (nih.gov) Clin Exp Dent Res. 2022 Feb;8(1):130-140. doi: 10.1002/cre2.501. Epub 2021 Oct 9.
Combined loss of expression of involucrin and cytokeratin 13 is associated with poor prognosis in squamous cell carcinoma of mobile tongue – PubMed (nih.gov) Head Neck. 2021 Nov;43(11):3374-3385. doi: 10.1002/hed.26826. Epub 2021 Aug 2.
Feasibility of a Portable Electronic Nose for Detection of Oral Squamous Cell Carcinoma in Sudan – PubMed (nih.gov) Healthcare (Basel). 2021 May 3;9(5):534. doi: 10.3390/healthcare9050534.
Combined In Situ Hybridization and Immunohistochemistry on Archival Tissues Reveals Stromal microRNA-204 as Prognostic Biomarker for Oral Squamous Cell Carcinoma – PubMed (nih.gov) Cancers (Basel). 2021 Mar 15;13(6):1307. doi: 10.3390/cancers13061307.
2020
Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells – PubMed (nih.gov) Pharmaceutics. 2020 Nov 6;12(11):1058. doi: 10.3390/pharmaceutics12111058.
Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics – PubMed (nih.gov)PLoS One. 2020 Sep 4;15(9):e0238591. doi: 10.1371/journal.pone.0238591. eCollection 2020.
A combined histo-score based on tumor differentiation and lymphocytic infiltrate is a robust prognostic marker for mobile tongue cancer – PubMed (nih.gov)Virchows Arch. 2020 Dec;477(6):865-872. doi: 10.1007/s00428-020-02875-9. Epub 2020 Jun 30.
Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009 – PubMed (nih.gov)Clin Exp Dent Res. 2020 Jun;6(3):356-362. doi: 10.1002/cre2.278. Epub 2020 Jan 12.
Helicobacter pylori was not detected in oral squamous cell carcinomas from cohorts of Norwegian and Nepalese patients – PubMed (nih.gov)Sci Rep. 2020 May 26;10(1):8737. doi: 10.1038/s41598-020-65694-7.
Loss of S100A14 expression at the tumor-invading front correlates with poor
differentiation and worse prognosis in oral squamous cell carcinoma. Pandey S, Osman TA, Sharma S, Vallenari EM, Shahdadfar A, Pun CB, Gautam DK, Uhlin-Hansen L, Rikardsen O, Johannessen AC, Costea DE, Sapkota D. Head Neck. 2020 Mar 23. doi: 10.1002/hed.26140. [Epub ahead of print] PubMed PMID: 32202693.
Use of nanomaterials in dentistry: covariates of risk and benefit perceptions among
dentists and dental hygienists in Norway. Xenaki V, Costea DE, Marthinussen MC, Cimpan MR, Åstrøm AN. Acta Odontol Scand. 2020 Mar;78(2):152-160. doi: 10.1080/00016357.2019.1668055. Epub 2019 Sep 27. PubMed
PMID: 31561718.
Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma associated fibroblasts. Zhang Z, Gao Z, Rajthala S, Sapkota D, Dongre H, Parajuli H, Suliman S, Das R, Li L, Bindoff LA, Costea DE, Liang X. Cell Mol Life Sci. 2020 Mar;77(6):1115-1133. doi: 10.1007/s00018-019-03209-y. Epub 2019 Jul 3. PubMed PMID: 31270582.
Knowledge about nanotechnology and intention to use nanomaterials: A
comparative study among dental students in Norway and Romania. Xenaki V, Marthinussen MC, Costea DE, Didilescu AC, Susin C, Cimpan MR, Åstrøm AN. Eur J Dent Educ. 2020 Feb;24(1):79-87. doi: 10.1111/eje.12470. Epub 2019 Oct 16. PubMed PMID: 31574582.
Grading of oral squamous cell carcinomas – Intra and interrater agreeability: Simpler is better? Steigen SE, Søland TM, Nginamau ES, Laurvik H, Costea DE, Johannessen AC, Jebsen P, Bjerkli IH, Uhlin-Hansen L, Hadler-Olsen E. J Oral Pathol Med. 2020 Jan 3. doi: 10.1111/jop.12990. [Epub ahead of print] PubMed PMID: 31899572.
Establishment of a novel cancer cell line derived from vulvar carcinoma associated with lichen sclerosus exhibiting a fibroblast-dependent tumorigenic potential. Dongre H, Rana N, Fromreide S, Rajthala S, Bøe Engelsen I, Paradis J, Gutkind JS, Vintermyr OK, Johannessen AC, Bjørge L, Costea DE. Exp Cell Res. 2020 Jan 1;386(1):111684. doi: 10.1016/j.yexcr.2019.111684. Epub 2019 Oct 23. PubMed PMID: 31654625.
2019
Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells. Suliman S, Ali HRW, Karlsen TA, Amiaud J, Mohamed-Ahmed S, Layrolle P, Costea DE, Brinchmann JE, Mustafa K. Sci Rep. 2019 Nov 5;9(1):16031. doi: 10.1038/s41598-019-52442-9. PubMed PMID: 31690774; PubMed Central PMCID:
PMC6831606.
Isolation and characterization of cells derived from human epithelial rests of
Malassez. Kitajima K, Das R, Liang X, Neppelberg E, Johannessen AC, Costea DE, Igarashi
M. Odontology. 2019 Jul;107(3):291-300. doi: 10.1007/s10266-018-0397-7.
Epub 2018 Nov 26. PubMed PMID: 30478679; PubMed Central PMCID: PMC6557869.
α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration. Zeltz C, Alam J, Liu H, Erusappan PM, Hoschuetzky H, Molven A, Parajuli H, Cukierman E, Costea DE, Lu N, Gullberg D. Cancers (Basel). 2019 Jun 1;11(6). pii: E765. doi: 10.3390/cancers11060765. PubMed PMID: 31159419; PubMed Central PMCID: PMC6627481.
Fibroblasts rescue oral squamous cancer cell from metformin-induced apoptosis via alleviating
metabolic disbalance and inhibiting AMPK pathway. Zhang Z, Liang X, Fan Y, Gao Z, Bindoff LA, Costea DE, Li L. Cell Cycle. 2019 May;18(9):949-962. doi: 10.1080/15384101.2019.1598727. Epub 2019 Apr 23. PubMed PMID: 31014173; PubMed Central PMCID: PMC6527302.
Expression profile and functional role of S100A14 in human cancer. Basnet S, Sharma S, Costea DE, Sapkota D. Oncotarget. 2019 Apr 26;10(31):2996-3012. doi: 10.18632/oncotarget.26861. eCollection 2019 Apr 26. Review. PubMed PMID: 31105881; PubMed Central PMCID: PMC6508202.
Effect of glycerol on reconstructed human oral mucosa. Kvalheim SF, Xenaki V, Kvalheim A, Lie SA, Marthinussen MC, Strand GV, Costea DE. Eur J Oral Sci. 2019 Feb;127(1):19-26. doi: 10.1111/eos.12590. Epub 2018 Nov 19. PubMed PMID: 30452098.
2018
Aberrant expression of vimentin predisposes oral premalignant lesion derived cells towards transformation. Dmello C, Sawant S, Chaudhari PR, Dongre H, Ahire C, D’Souza ZC, Charles SE,
Rane P, Costea DE, Chaukar D, Kane S, Vaidya M. Exp Mol Pathol. 2018 Dec;105(3):243-251. doi: 10.1016/j.yexmp.2018.08.010. Epub 2018 Sep 4. PubMed PMID: 30189187.
Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography. Guerreiro EM, Vestad B, Steffensen LA, Aass HCD, Saeed M, Øvstebø R, Costea DE, Galtung HK, Søland TM. PLoS One. 2018 Sep 27;13(9):e0204276. doi: 10.1371/journal.pone.0204276. eCollection 2018. PubMed PMID: 30260987; PubMed Central PMCID: PMC6160036.
https://www.ncbi.nlm.nih.gov/pubmed/30177913Oral Tongue Malignancies in Autoimmune Polyendocrine Syndrome Type 1. Bruserud Ø, Costea DE, Laakso S, Garty BZ, Mathisen E, Mäkitie A, Mäkitie O, Husebye ES. Front Endocrinol (Lausanne). 2018 Aug 17;9:463. doi: 10.3389/fendo.2018.00463. eCollection 2018. PubMed PMID: 30177913; PubMed Central PMCID: PMC6109689.
2017
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor – β1 (TGF-β1) and potential effects on migration and invasion. Magnussen SN, Hadler-Olsen E, Costea DE, Berg E, Jacobsen CC, Mortensen B, Salo T, Martinez-Zubiaurre I, Winberg JO, Uhlin-Hansen L, Svineng G., BMC Cancer. 2017 May 19;17(1):350. doi: 10.1186/s12885-017-3349-7.
Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression. Parajuli H, Teh MT, Abrahamsen S, Christoffersen I, Neppelberg E, Lybak S, Osman T, Johannessen AC, Gullberg D, Skarstein K, Costea DE., J Oral Pathol Med. 2017 Apr;46(4):267-275. doi: 10.1111/jop.12493.
Nano-TiO2 penetration of oral mucosa: in vitro analysis using 3D organotypic human buccal mucosa models. Konstantinova V, Ibrahim M, Lie SA, Birkeland ES, Neppelberg E, Marthinussen MC, Costea DE, Cimpan MR, J Oral Pathol Med. 2017 Mar;46(3):214-222. doi: 10.1111/jop.12469.
2016
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes. Suliman S, Mustafa K, Krueger A, Steinmüller-Nethl D, Finne-Wistrand A, Osdal T, Hamza AO, Sun Y, Parajuli H, Waag T, Nickel J, Johannessen AC, McCormack E, Costea DE. Biomaterials. 2016 Jul;95:11-21. doi: 10.1016/j.biomaterials.2016.04.002.
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds. Suliman S, Parajuli H, Sun Y, Johannessen AC, Finne-Wistrand A, McCormack E, Mustafa K, Costea DE. Head Neck. 2016 Apr;38 Suppl 1:E1177-87. doi: 10.1002/hed.24187.
Gene Expression and Proteome Analysis as Sources of Biomarkers in Basal Cell Carcinoma. Lupu M, Caruntu C, Ghita MA, Voiculescu V, Voiculescu S, Rosca AE, Caruntu A, Moraru L, Popa IM, Calenic B, Greabu M, Costea DE. Dis Markers. 2016;2016:9831237. doi: 10.1155/2016/9831237. Review.
Establishment of 3D Co-Culture Models from Different Stages of Human Tongue Tumorigenesis: Utility in Understanding Neoplastic Progression. Sawant S, Dongre H, Singh AK, Joshi S, Costea DE, Mahadik S, Ahire C, Makani V, Dange P, Sharma S, Chaukar D, Vaidya M. PLoS One. 2016 Aug 8;11(8):e0160615. doi: 10.1371/journal.pone.0160615.
Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma. Biddle A, Gammon L, Liang X, Costea DE, Mackenzie IC., EBioMedicine. 2016 Jan 9;4:138-45. doi: 10.1016/j.ebiom.2016.01.007. eCollection 2016 Feb.
In Vivo Host Response and Degradation of Copolymer Scaffolds Functionalized with Nanodiamonds and Bone Morphogenetic Protein 2. Suliman S, Sun Y, Pedersen TO, Xue Y, Nickel J, Waag T, Finne-Wistrand A, Steinmüller-Nethl D, Krueger A, Costea DE, Mustafa K. , Adv Healthc Mater. 2016 Mar;5(6):730-42. doi: 10.1002/adhm.201500723.
Vimentin-mediated regulation of cell motility through modulation of beta4 integrin protein levels in oral tumor derived cells. Dmello C, Sawant S, Alam H, Gangadaran P, Tiwari R, Dongre H, Rana N, Barve S, Costea DE, Chaukar D, Kane S, Pant H, Vaidya M.Int J Biochem Cell Biol. 2016 Jan;70:161-72. doi: 10.1016/j.biocel.2015.11.015.
2015
Sapkota D, Bruland O, Parajuli H, Osman TA, Teh MT, Johannessen AC, Costea DE.
S100A16 promotes differentiation and contributes to a less aggressive tumor
phenotype in oral squamous cell carcinoma. BMC Cancer. 2015 Sep 9;15:631. doi:
10.1186/s12885-015-1622-1. PubMed PMID: 26353754; PubMed Central PMCID:
PMC4564982.
Osman TA, Parajuli H, Sapkota D, Ahmed IA, Johannessen ACh, Costea DE. The
low-affinity nerve growth factor receptor p75NTR identifies a transient stem
cell-like state in oral squamous cell carcinoma cells. J Oral Pathol Med. 2015
Jul;44(6):410-9. doi: 10.1111/jop.12251. Epub 2014 Sep 12. PubMed PMID: 25212757.
Min A, Zhu C, Peng S, Rajthala S, Costea DE, Sapkota D. MicroRNAs as Important
Players and Biomarkers in Oral Carcinogenesis. Biomed Res Int. 2015;2015:186904.
doi: 10.1155/2015/186904. Epub 2015 Oct 4. Review. PubMed PMID: 26504785; PubMed
Central PMCID: PMC4609509.
2014
Liang X, Graham KA, Johannessen AC, Costea DE, Labeed FH. Human oral cancer
cells with increasing tumorigenic abilities exhibit higher effective membrane
capacitance. Integr Biol (Camb). 2014 May;6(5):545-54. doi: 10.1039/c3ib40255j.
PubMed PMID: 24663430.
Liang X, Osman TA, Sapkota D, Neppelberg E, Lybak S, Liavaag PG, Johannessen
AC, Jacobsen HK, Enger PØ, Costea DE, Wang J. Rapid adherence to collagen IV
enriches for tumour initiating cells in oral cancer. Eur J Cancer. 2014
Dec;50(18):3262-70. doi: 10.1016/j.ejca.2014.09.010. Epub 2014 Oct 10. PubMed
PMID: 25310894.
Yang N, Yan T, Zhu H, Liang X, Leiss L, Sakariassen PØ, Skaftnesmo KO, Huang
B, Costea DE, Enger PØ, Li X, Wang J. A co-culture model with brain
tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in
glioblastoma. J Transl Med. 2014 Oct 4;12:278. doi: 10.1186/s12967-014-0278-y.
PubMed PMID: 25280402; PubMed Central PMCID: PMC4198700.
2013
Costea DE, Hills A, Osman AH, Thurlow J, Kalna G, Huang X, Pena Murillo C,
Parajuli H, Suliman S, Kulasekara KK, Johannessen AC, Partridge M. Identification
of two distinct carcinoma-associated fibroblast subtypes with differential
tumor-promoting abilities in oral squamous cell carcinoma. Cancer Res. 2013 Jul
1;73(13):3888-901. doi: 10.1158/0008-5472.CAN-12-4150. Epub 2013 Apr 18. PubMed
PMID: 23598279.
Kidwai F, Costea DE, Hutchison I, Mackenzie I. The effects of CD44
down-regulation on stem cell properties of head and neck cancer cell lines. J
Oral Pathol Med. 2013 Oct;42(9):682-90. doi: 10.1111/jop.12076. Epub 2013 Apr 30.
PubMed PMID: 23627635.
Salo S, Bitu C, Merkku K, Nyberg P, Bello IO, Vuoristo J, Sutinen M,
Vähänikkilä H, Costea DE, Kauppila JH, Lehenkari P, Dayan D, Vered M, Risteli J,
Salo T. Human bone marrow mesenchymal stem cells induce collagen production and
tongue cancer invasion. PLoS One. 2013 Oct 21;8(10):e77692. doi:
10.1371/journal.pone.0077692. eCollection 2013. Erratum in: PLoS One. 2013;8(11).
doi:10.1371/annotation/2bacf09d-7bb8-43ac-a098-b3b9e486d854. Kauppila, Joonas
[corrected to Kauppila, Joonas H]. PubMed PMID: 24204919; PubMed Central PMCID:
PMC3804615.
Hwang S, Mahadevan S, Qadir F, Hutchison IL, Costea DE, Neppelberg E, Liavaag
PG, Waseem A, Teh MT. Identification of FOXM1-induced epigenetic markers for head
and neck squamous cell carcinomas. Cancer. 2013 Dec 15;119(24):4249-58. doi:
10.1002/cncr.28354. Epub 2013 Oct 1. PubMed PMID: 24114764.
Sapkota D, Costea DE, Ibrahim SO, Johannessen AC, Bruland O. S100A14
interacts with S100A16 and regulates its expression in human cancer cells. PLoS
One. 2013 Sep 27;8(9):e76058. doi: 10.1371/journal.pone.0076058. eCollection
PubMed PMID: 24086685; PubMed Central PMCID: PMC3785438.
Osman TA, Øijordsbakken G, Costea DE, Johannessen AC. Successful triple
immunoenzymatic method employing primary antibodies from same species and same
immunoglobulin subclass. Eur J Histochem. 2013 Sep 16;57(3):e22. doi:
10.4081/ejh.2013.e22. PubMed PMID: 24085271; PubMed Central PMCID: PMC3794353.
2012
Dabija-Wolter G, Bakken V, Cimpan MR, Johannessen AC, Costea DE. In vitro
reconstruction of human junctional and sulcular epithelium. J Oral Pathol Med.
2013 May;42(5):396-404. doi: 10.1111/jop.12005. Epub 2012 Sep 5. PubMed PMID:
22947066; PubMed Central PMCID: PMC3664418.
Litlekalsoy J, Hostmark JG, Costea DE, Illemann M, Laerum OD. Time-dependent
biological differences in molecular markers of high-grade urothelial cancer over
7 decades (ras proteins, pTEN, uPAR, PAI-1 and MMP-9). Virchows Arch. 2012
Nov;461(5):541-51. doi: 10.1007/s00428-012-1323-y. Epub 2012 Oct 6. PubMed PMID:
23052373.
Dayan D, Salo T, Salo S, Nyberg P, Nurmenniemi S, Costea DE, Vered M.
Molecular crosstalk between cancer cells and tumor microenvironment components
suggests potential targets for new therapeutic approaches in mobile tongue
cancer. Cancer Med. 2012 Oct;1(2):128-40. doi: 10.1002/cam4.24. Epub 2012 Aug 16.
PubMed PMID: 23342263; PubMed Central PMCID: PMC3544451.
Teh MT, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Purdie K, Harwood
C, Wan H, Odell EW, Hackshaw A, Waseem A. Exploiting FOXM1-orchestrated molecular
network for early squamous cell carcinoma diagnosis and prognosis. Int J Cancer.
2013 May 1;132(9):2095-106. doi: 10.1002/ijc.27886. Epub 2012 Oct 25. PubMed
PMID: 23034676.
Osman TA, Costea DE, Johannessen AC. The use of salivary cytokines as a
screening tool for oral squamous cell carcinoma : A review of the literature. J
Oral Maxillofac Pathol. 2012 May;16(2):256-61. doi: 10.4103/0973-029X.99083.
PubMed PMID: 22923900; PubMed Central PMCID: PMC3424944.
2011
Dabija-Wolter G, Sapkota D, Cimpan MR, Neppelberg E, Bakken V, Costea DE.
Limited in-depth invasion of Fusobacterium nucleatum into in vitro reconstructed
human gingiva. Arch Oral Biol. 2012 Apr;57(4):344-51. doi:
10.1016/j.archoralbio.2011.09.015. Epub 2011 Oct 24. PubMed PMID: 22024403.
Biddle A, Liang X, Gammon L, Fazil B, Harper LJ, Emich H, Costea DE,
Mackenzie IC. Cancer stem cells in squamous cell carcinoma switch between two
distinct phenotypes that are preferentially migratory or proliferative. Cancer
Res. 2011 Aug 1;71(15):5317-26. doi: 10.1158/0008-5472.CAN-11-1059. Epub 2011 Jun
- PubMed PMID: 21685475.
Sapkota D, Bruland O, Costea DE, Haugen H, Vasstrand EN, Ibrahim SO. S100A14
regulates the invasive potential of oral squamous cell carcinoma derived
cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1
and MMP9. Eur J Cancer. 2011 Mar;47(4):600-10. doi: 10.1016/j.ejca.2010.10.012.
Epub 2010 Nov 10. PubMed PMID: 21074410.
Wiklund ED, Gao S, Hulf T, Sibbritt T, Nair S, Costea DE, Villadsen SB,
Bakholdt V, Bramsen JB, Sørensen JA, Krogdahl A, Clark SJ, Kjems J. MicroRNA
alterations and associated aberrant DNA methylation patterns across multiple
sample types in oral squamous cell carcinoma. PLoS One. 2011;6(11):e27840. doi:
10.1371/journal.pone.0027840. Epub 2011 Nov 22. PubMed PMID: 22132151; PubMed
Central PMCID: PMC3222641.
Sapkota D, Costea DE, Blø M, Bruland O, Lorens JB, Vasstrand EN, Ibrahim SO.
S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest.
Oral Oncol. 2012 Mar;48(3):219-25. doi: 10.1016/j.oraloncology.2011.10.001. Epub
2011 Oct 26. PubMed PMID: 22032898.
Mulhall HJ, Labeed FH, Kazmi B, Costea DE, Hughes MP, Lewis MP. Cancer,
pre-cancer and normal oral cells distinguished by dielectrophoresis. Anal Bioanal
Chem. 2011 Nov;401(8):2455-63. doi: 10.1007/s00216-011-5337-0. Epub 2011 Aug 30.
PubMed PMID: 21877186.
2010 and beyond
Harper LJ, Costea DE, Gammon L, Fazil B, Biddle A, Mackenzie IC. Normal and
malignant epithelial cells with stem-like properties have an extended G2 cell
cycle phase that is associated with apoptotic resistance. BMC Cancer. 2010 Apr
28;10:166. doi: 10.1186/1471-2407-10-166. PubMed PMID: 20426848; PubMed Central
PMCID: PMC2868812.
Berge G, Costea DE, Berg M, Rasmussen H, Grotterød I, Lothe RA, Mælandsmo GM,
Flatmark K. Coexpression and nuclear colocalization of metastasis-promoting
protein S100A4 and p53 without mutual regulation in colorectal carcinoma. Amino
Acids. 2011 Oct;41(4):875-84. doi: 10.1007/s00726-010-0514-6. Epub 2010 Feb 27.
PubMed PMID: 20191297.
Lukandu OM, Neppelberg E, Vintermyr OK, Johannessen AC, Costea DE. Khat
alters the phenotype of in vitro-reconstructed human oral mucosa. J Dent Res.
2010 Mar;89(3):270-5. doi: 10.1177/0022034509354980. Epub 2009 Dec 31. PubMed
PMID: 20044580.
Costea DE, Lukandu O, Bui L, Ibrahim MJ, Lygre R, Neppelberg E, Ibrahim SO,
Vintermyr OK, Johannessen AC. Adverse effects of Sudanese toombak vs. Swedish
snuff on human oral cells. J Oral Pathol Med. 2010 Feb;39(2):128-40. doi:
10.1111/j.1600-0714.2009.00825.x. Epub 2009 Oct 4. PubMed PMID: 19804503.
Kulasekara KK, Lukandu OM, Neppelberg E, Vintermyr OK, Johannessen AC, Costea
- Cancer progression is associated with increased expression of basement
membrane proteins in three-dimensional in vitro models of human oral cancer. Arch
Oral Biol. 2009 Oct;54(10):924-31. doi: 10.1016/j.archoralbio.2009.07.004. Epub
2009 Aug 11. PubMed PMID: 19674736.
Lukandu OM, Bredholt T, Neppelberg E, Gjertsen BT, Johannessen AC, Vintermyr
OK, Costea DE. Early loss of mitochondrial inner transmembrane potential in
khat-induced cell death of primary normal human oral cells. Toxicology. 2009 Sep
19;263(2-3):108-16. doi: 10.1016/j.tox.2009.06.024. Epub 2009 Jul 8. PubMed PMID:
19591894.
Dabija-Wolter G, Cimpan MR, Costea DE, Johannessen AC, Sørnes S, Neppelberg
E, Al-Haroni M, Skaug N, Bakken V. Fusobacterium nucleatum enters normal human
oral fibroblasts in vitro. J Periodontol. 2009 Jul;80(7):1174-83. doi:
10.1902/jop.2009.090051. PubMed PMID: 19563299.
Costea DE, Gammon L, Kitajima K, Harper L, Mackenzie IC. Epithelial stem
cells and malignancy. J Anat. 2008 Jul;213(1):45-51. doi:
10.1111/j.1469-7580.2008.00895.x. Review. PubMed PMID: 18638069; PubMed Central
PMCID: PMC2475555.
Gaballah K, Costea DE, Hills A, Gollin SM, Harrison P, Partridge M. Tissue
engineering of oral dysplasia. J Pathol. 2008 Jul;215(3):280-9. doi:
10.1002/path.2360. PubMed PMID: 18484684.
Lukandu OM, Costea DE, Neppelberg E, Johannessen AC, Vintermyr OK. Khat
(Catha edulis) induces reactive oxygen species and apoptosis in normal human oral
keratinocytes and fibroblasts. Toxicol Sci. 2008 Jun;103(2):311-24. doi:
10.1093/toxsci/kfn044. Epub 2008 Feb 29. PubMed PMID: 18310640.
Lukandu OM, Costea DE, Dimba EA, Neppelberg E, Bredholt T, Gjertsen BT,
Vintermyr OK, Johannessen AC. Khat induces G1-phase arrest and increased
expression of stress-sensitive p53 and p16 proteins in normal human oral
keratinocytes and fibroblasts. Eur J Oral Sci. 2008 Feb;116(1):23-30. doi:
10.1111/j.1600-0722.2007.00508.x. PubMed PMID: 18186728.
Partridge M, Costea DE, Huang X. The changing face of p53 in head and neck
cancer. Int J Oral Maxillofac Surg. 2007 Dec;36(12):1123-38. Epub 2007 Sep 17.
Review. PubMed PMID: 17875383.
Neppelberg E, Costea DE, Vintermyr OK, Johannessen AC. Dual effects of sodium
lauryl sulphate on human oral epithelial structure. Exp Dermatol. 2007
Jul;16(7):574-9. PubMed PMID: 17576237.
Costea DE, Tsinkalovsky O, Vintermyr OK, Johannessen AC, Mackenzie IC. Cancer
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